The 1991-92 season was a successful one for Sampdoria. The team finished fourth in the Serie A, securing a spot in the following season's UEFA Cup. They also reached the quarterfinals of the Coppa Italia, where they lost to Lazio.

Sampdoria's star player during the 1991-92 season was forward Roberto Mancini, who scored 19 goals in all competitions. Mancini was a key part of the team's attack and was known for his technical ability and creative play. Other key players for Sampdoria during the season included midfielders Attilio Lombardo and Moreno Mannini, and defenders Pietro Vierchowod and Moreno Torricelli.

Under manager Sven-Goran Eriksson, Sampdoria played a possession-based, attacking style of soccer. The team was known for their creative attacking play and their ability to score goals from a variety of different sources.

Overall, the 1991-92 season was a successful one for Sampdoria. They secured a place in the UEFA Cup and reached the quarterfinals of the Coppa Italia, and their performances throughout the season demonstrated their place among the top teams in Italian soccer. Despite their loss in the Coppa Italia, the team's success in other competitions made it a memorable season for Sampdoria and their fans.